![]() En diarrea asociada a antibióticos y a Clostridium difficile, los metanálisis muestran reducción del riesgo entre el 50-60%, con recomendación fuerte para Lactobacillus rhamnosus GG y Saccharomyces boulardii con un NNT de 10 (IC 95% 7-12). Resultados: En diarrea aguda, metaanálisis muestran disminución de la duración en un día (IC 95% 15,9 a 33,6 horas) y disminución del riesgo de prolongación en los siguientes 4 y 7 días, con recomendaciones fuertes y evidencia moderada para Lactobacillus rhamnosus GG y Saccharomyces boulardii. Métodos: Se realizó una revisión de la literatura incluyendo solo metaanálisis y revisiones sistemáticas en los últimos diez años acerca del uso de probióticos en diarrea aguda, diarrea asociada a antibióticos y Clostridium difficile y diarrea nosocomial. Existen numerosos estudios acerca de su uso en enfermedad diarreica en pediatría, por lo que se hace necesario evaluar la evidencia. Introducción: Los probióticos son microorganismos vivos, que administrados en cantidades adecuadas proveen una acción benéfica en el ser humano. ![]() Probióticos, pediatría, diarrea, antibióticos, infección hospitalaria Resumen Hospital universitario Fundación Santa Fe de Bogotá ![]()
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